About Creatinine Clearance Calculator
When to Use
- To estimate creatinine clearance in adults
- For drug dosing adjustments
- To assess kidney function
- When direct measurement is not available
Pearls/Pitfalls
- Less accurate in elderly patients
- May overestimate GFR in obesity
- Not validated for acute kidney injury
- Use actual body weight for underweight patients
- Use ideal body weight for normal/overweight patients
- Use adjusted body weight for obese patients
Why Use
- Widely used and accepted formula
- Simple to calculate
- Requires readily available data
- Useful for medication dosing
- More accurate than serum creatinine alone
About the Formula
Cockcroft-Gault Equation
Developed in 1973 by Donald W. Cockcroft and M. Henry Gault, this equation estimates creatinine clearance using serum creatinine, age, weight, and gender.
Formula: CrCl = [(140 - age) × weight × (0.85 if female)] / (72 × Scr)
Calculate Creatinine Clearance
Results
Renal Function Categories
| CrCl (mL/min) | Category |
|---|---|
| ≥ 90 | Normal |
| 60-89 | Mild Impairment |
| 30-59 | Moderate Impairment |
| 15-29 | Severe Impairment |
| < 15 | Kidney Failure |